Santos Guest House lies in the Estrela district of Lisbon, within reach of entertainment venues like Arco do Triunfo, about a 25-minute walk away.

Fachada do Edificio na Rua do Sacramento a Lapa 24 is located around 5 minutes by car from this Lisbon guest house, and such natural sites as Miradouro Sao Pedro de Alcantara is a 5-minute ride away. The nearby cultural sights are Oficina Impossivel (650 metres) and the Portuguese Calouste Gulbenkian Museum (3.1 km). National Museum of Ancient Art, a well-known local spot, is also quite close to the hotel. This Lisbon property is about 200 metres from Lapa bus station.

While staying at Santos Guest House, guests can choose from dining options nearby, such as Sr. Vinho, located a mere 300 metres away, or Boutique Doce at a 5-minute walking distance.